What supports near-term growth?
- Management maintains its double-digit revenue growth guidance for fiscal 2026 and expects double-digit growth in both product sales and business development (BD) revenue.
- Existing innovative drugs continue to grow: flumatinib, Heng Mu, Fulai Mei and semaglutide each grew by more than 30% in the first half of 2026. Management believes sales of marketed innovative drugs are still far from their peak.
- Management's sales target for core product Ameile is RMB 8 billion by 2030; if future combination therapy strategies are taken into account, sales could reach RMB 10 billion.
How will the new drug portfolio expand from 9 to 30 products?
- The company reiterated its target of having 30 marketed innovative drugs by 2030, up from 9 currently. Management expects 5 new products to be approved in 2027 and plans to submit 8 to 10 investigational new drug applications and launch multiple phase III trials each year.
- A marketing application has been submitted for an injectable GLP-1/GIP drug, which the company expects to launch in 2027. Promotion will use the existing endocrinology hospital sales network while expanding retail channels.
- Goldman Sachs expects BD revenue to grow steadily, with B7-H3-related milestone payments and future sales royalties becoming an increasingly important source of contributions from 2029 onward.
How far has the ADC pipeline progressed?
- Biologics license applications for the B7-H3 ADC risvutatug rezetecan in two indications, small-cell lung cancer and osteosarcoma, are under review in China.
- In a first-in-human phase I study, the EGFR/c-MET bispecific ADC HS-20122 achieved an objective response rate of 61.3% and a six-month progression-free survival rate of 75.3% in patients with EGFR-mutated non-small-cell lung cancer whose EGFR inhibitor treatment had failed. The data remain early, and cross-trial comparisons require caution.
- Another CDH17 ADC, HS-20110, is undergoing a phase Ib study in China; the company also primarily positions its EGFR/c-MET bispecific antibody for use in combination with Ameile in first-line treatment of non-small-cell lung cancer and is exploring other indications.
How does Goldman Sachs value the company, and what constraints does it watch?
- Goldman Sachs rates Hansoh Pharma Buy, with a 12-month price target of HK$52.70. Its sum-of-the-parts valuation includes a discounted cash flow value of HK$287 billion for the innovative drug business and a value of HK$32.6 billion for the generics business, calculated at 10 times expected 2026 earnings.
- Risks listed by Goldman Sachs include lower-than-expected generic drug sales following volume-based procurement, slower sales ramp-up after new drug launches, setbacks in innovative drug R&D, and lower-than-expected revenue from global pipeline collaborations.