Research library

1,751 reports · By date added

J.P. Morgan: Kolon Biotech’s phase III lung cancer data: progression-free survival extended, with the efficacy advantage driven by more durable disease control

OptiTROP-Lung06 showed that sac-TMT plus pembrolizumab achieved median progression-free survival of 15.0 months in first-line treatment of PD-L1-negative advanced non-squamous non-small cell lung cancer, versus 5.7 months in the control group. JPMorgan is optimistic about its first-line treatment opportunity, but overall survival data remain immature, and median progression-free survival may fluctuate as the data mature.

J.P. Morgan: Akeso’s phase III biliary tract cancer trial meets survival endpoint, but strong control arm narrows relative advantage

Ivonescimab plus chemotherapy extended median overall survival by 2.8 months compared with durvalumab plus chemotherapy. The result was statistically significant but fell short of JPMorgan’s previous optimistic scenario. Phase II lung cancer data for another PD-1/VEGF bispecific antibody support the drug class; the competitive landscape remains to be clarified by phase III data.

Morgan Stanley: Kelun Pharmaceutical’s first-line lung cancer trial exceeds expectations: progression-free survival extended, but overall survival data remain early

Morgan Stanley believes sac-TMT plus pembrolizumab delivered a progression-free survival benefit beyond recent market expectations in a Chinese phase III lung cancer trial. Its safety profile also supports its potential to replace chemotherapy; efficacy in patients with brain metastases and results in certain subgroups remain important questions.

Morgan Stanley: China’s pharmaceutical exports grow, but pressure on API prices persists

Pharmaceutical exports rose 10.5% year on year in the first three quarters of 2026, but the trade deficit still widened to 21 billion US dollars. Morgan Stanley says excess capacity and low utilization continue to suppress active pharmaceutical ingredient (API) prices, prompting some manufacturers to move into finished formulations or CDMO services.

Morgan Stanley: Sinoma Science & Technology’s third-quarter profit rises 46% year on year, broadly flat quarter on quarter

Higher glass fiber volumes and prices, together with higher lithium-ion battery separator volumes and prices in the third quarter, improved Sinoma Science & Technology’s profitability in the first three quarters. However, third-quarter revenue and net profit were both broadly flat quarter on quarter, and Morgan Stanley viewed the results as slightly below market consensus.

Nomura: EVE Energy: Overseas customers improve profitability, so why did Nomura raise its earnings forecasts but cut its price target?

A higher contribution from overseas customers improved the third-quarter gross margin; the company raised its 2027 shipment targets, and Nomura consequently revised its earnings forecasts upward. But the tax burden, dilution from the trading business and cash spending on capacity expansion are constraints, while industry policy pressure also prompted Nomura to lower its valuation multiples.